1
general::
1. Grow or get taller very rapidly, as in She's really shot up in the last year, and now she's taller than her mother. [First half of 1500s] 2. Riddle with bullets; damage or terrorize with gunfire. For example, I liked the scene in which the cowboy stomps into the saloon, gets drunk, and shoots the place up. [Late 1800s] 3. Inject a drug intravenously, especially an illegal drug. For example, The police caught him shooting up and arrested him. [Slang; first half of 1900s]
American Heritage Idioms
2
general::
Phrase(s): shoot up
Sl. to take drugs by injection. • Wallace was caught by the cops shooting up in the high school rest room.
McGrawhill's American Idioms And Phrasal Verbs